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Panduan penyiapan dan pemberian terapi medikasi
Panduan penyiapan dan pemberian terapi medikasi
Dopamine Hydrocloride
Penyiapan
Sediaan
- 40 mg/ml
Rekomendasi Pengenceran (Konsentrasi)
<10mg/ml
Pelarut
- D5%
- NaCl 0.9%
- RL
- WI
Pemberian
Rekomendasi Akses
IV besar atau central
dengan pump (titrasi)
dengan pump (titrasi)
Rekomendasi Durasi Pemberian
5-10 mcg/kg/menit hingga 50 mcg/kg/menit
Stabilitas Obat Setelah Rekonstruksi
48 jam pada suhu 30 derajat celcius dan paparan cahaya minimum
Keamanan
pH
2,5-5
pH risiko tinggi (<4 / >9)
Osmolaritas Sebelum Pengenceran
619mOsm/kg
Osmolaritas sedang (600-900)
Perhatikan cara pemberian
Perhatikan cara pemberian
Osmolaritas Sesudah Pengenceran
konsentrasi 10mg/ml = 277mOsm/kg
Osmolaritas rendah (<600)
Phlebitis
Tidak
Inkompatibilitas
-
Sodium bicarbonate
-
Acyclovir sodium
-
Amphotericin B
-
Alteplase
-
Ampicillin sodium
-
Gentamicin sulfate
-
Penicillin G potassium
-
Pantoprazole sodium
-
Aldesleukin
-
Furosemide
-
Ibuprofen lysinat
-
Indomethacin sodium trihydrate
-
Insulin
- Quinupristin–dalfopristin
Klasifikasi GHS
Irritant
Health Hazard
Environment Hazard
Manifestasi GHS
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
Sumber
- Brosur obat dari PT Dexa Medika Palembang-Indonesia
- https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1f306ad2-3606-4525-5a8a-ce78f426c1a2
- American Society of Health-System Pharmacists. 2021. ASHP® Injectable Drug Information: A Comprehensive Guide to Compatibility and Stability. 2021 Edition. eBook. American Society of Health-System Pharmacists. ISBN: 978-1-58528-690-4. doi.org/10.37573/9781585286850"